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SaveAskTourHide$450,0004 Days On Site354 Main StreetPoughkeepsie, NY 12601
For Sale|Mixed Use|Active 0
Beds0
Total Baths7,800
SqFt$58
/SqFtCounty:Dutchess Listing courtesy of KW MidHudson dminichino@kwcommercial.com Call Now: (845) 516-5123Is this the listing for you? We can help make it yours.(845) 516-5123
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Monthly Payment (Est.)
Enter an interest rate to see your estimated monthly payment.Calculator powered by Showcase IDX, a Constellation1 Company. Copyright ©2026 Information is deemed reliable but not guaranteed.354 Main Street, Poughkeepsie, presents an exceptional value-add investment opportunity characterized by immediate operational cash flow paired with substantial equity-building upside. Built in 1900, this three-story mixed-use brick structure encompasses approximately 7,800 square feet of total space situated on a compact 0.07-acre parcel, delivering significant presence within a high-density urban district. The property is currently configured into two distinct functional units, establishing a versatile framework for real estate developers, investors, or owner-operators looking to capitalize on Poughkeepsie's ongoing downtown revitalization and strong demand for modernized commercial and residential inventory.
The ground-floor unit is currently occupied by an established medical practice operating under a flexible month-to-month lease agreement. This existing tenancy provides a valuable holding income stream from day one while affording a incoming owner complete strategic flexibility. A buyer can elect to retain the current tenant under a renegotiated long-term commercial lease, adjust rental rates to current market levels, or re-occupy the high-visibility street-level footprint for their own commercial enterprise. High foot traffic counts, strong vehicle exposure, direct storefront access, and surrounding civic institutions ensure long-term commercial viability for this lower level.
Spanning the entire second and third floors, the upper unit comprises an expansive, light-filled, time capsule of a space. Featuring high ceilings, historic structural character, and generous proportions, this area serves as a blank canvas ready for a full custom buildout tailored to a buyer's specific investment goals. Under municipal zoning guidelines, the upper floors offer two clear development trajectories: a multi-unit residential conversion—transforming the raw square footage into high-end rental apartments or a spacious live-work duplex—or a commercial expansion to house executive office suites, professional services, creative studios, or wellness facilities.
Offered strictly in as-is condition, 354 Main Street requires a comprehensive interior and exterior aesthetic overhaul. Investors can force substantial forced equity appreciation by modernizing the building’s exterior facade, updating window assemblies, and upgrading common building systems and mechanicals. Elevating the property's curb appeal along Main Street will directly enhance tenant recruitment and maximize overall capitalization rates.
Location is a central asset for this parcel. Situated within minutes of the Poughkeepsie Metro-North and Amtrak train station, the property offers direct transit access to New York City and Albany. Furthermore, its immediate proximity to Mid-Hudson Regional Hospital, Vassar Brothers Medical Center, local municipal offices, and higher education institutions like Vassar College and Dutchess Community College guarantees a consistent pool of prospective commercial and residential tenants. With its established ground-floor income, expansive raw upper floors, and prime arterial location, 354 Main Street represents a premier rehabilitation project ready for immediate transformation.
SaveAskTourHideListing SnapshotPrice $450,000Days On Site 4 DaysBedrooms N/AInside Area (SqFt) 7,800 sqftTotal Baths N/AFull Baths N/APartial Baths N/ALot Size 0.07 AcresYear Built N/AMLS Number 1069225Status ActiveProperty Tax $12,797.07HOA/Condo/Coop Fees N/ASq Ft Source N/AFriends & FamilyRecent Activity3 days ago Status changed to Active 3 days ago Price changed to $450,000 3 days ago Listing updated with changes from the MLS 4 days ago Listing first seen on site
General FeaturesAcres 0.07Number Of Stories 3Property Sub Type Mixed UseSewer Public SewerSqFt Total 7800Utilities Cable ConnectedElectricity ConnectedPhone ConnectedSewer ConnectedWater ConnectedWater Source PublicInterior FeaturesBasement PartialUnfinishedCooling Central AirFlooring HardwoodVinylHeating OilSaveAskTourHideExterior FeaturesConstruction Details BlockBrickCommunity FeaturesSchool District Poughkeepsie CitySchoolsSchool DistrictPoughkeepsie CityElementary SchoolUnknownMiddle SchoolUnknownHigh SchoolUnknown Listing courtesy of KW MidHudson dminichino@kwcommercial.com
Based on information submitted to the MLS GRID as of 2026-11-04 11:09 PM EST.
All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied
Open House Information is subject to change without notice. All information should be independently reviewed
and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information. Neighborhood & CommuteSource: WalkscoreDisclosure: Community information and market data powered by Constellation Data Labs. Information is deemed reliable but not guaranteed.SaveAskTourHide
354 Main StreetPoughkeepsie, NY 12601
Mortgage Calculator
Monthly Payment (Est.)
Enter an interest rate to see your estimated monthly payment.354 Main Street, Poughkeepsie, presents an exceptional value-add investment opportunity characterized by immediate operational cash flow paired with substantial equity-building upside. Built in 1900, this three-story mixed-use brick structure encompasses approximately 7,800 square feet of total space situated on a compact 0.07-acre parcel, delivering significant presence within a high-density urban district. The property is currently configured into two distinct functional units, establishing a versatile framework for real estate developers, investors, or owner-operators looking to capitalize on Poughkeepsie's ongoing downtown revitalization and strong demand for modernized commercial and residential inventory. The ground-floor unit is currently occupied by an established medical practice operating under a flexible month-to-month lease agreement. This existing tenancy provides a valuable holding income stream from day one while affording a incoming owner complete strategic flexibility. A buyer can elect to retain the current tenant under a renegotiated long-term commercial lease, adjust rental rates to current market levels, or re-occupy the high-visibility street-level footprint for their own commercial enterprise. High foot traffic counts, strong vehicle exposure, direct storefront access, and surrounding civic institutions ensure long-term commercial viability for this lower level. Spanning the entire second and third floors, the upper unit comprises an expansive, light-filled, time capsule of a space. Featuring high ceilings, historic structural character, and generous proportions, this area serves as a blank canvas ready for a full custom buildout tailored to a buyer's specific investment goals. Under municipal zoning guidelines, the upper floors offer two clear development trajectories: a multi-unit residential conversion—transforming the raw square footage into high-end rental apartments or a spacious live-work duplex—or a commercial expansion to house executive office suites, professional services, creative studios, or wellness facilities. Offered strictly in as-is condition, 354 Main Street requires a comprehensive interior and exterior aesthetic overhaul. Investors can force substantial forced equity appreciation by modernizing the building’s exterior facade, updating window assemblies, and upgrading common building systems and mechanicals. Elevating the property's curb appeal along Main Street will directly enhance tenant recruitment and maximize overall capitalization rates. Location is a central asset for this parcel. Situated within minutes of the Poughkeepsie Metro-North and Amtrak train station, the property offers direct transit access to New York City and Albany. Furthermore, its immediate proximity to Mid-Hudson Regional Hospital, Vassar Brothers Medical Center, local municipal offices, and higher education institutions like Vassar College and Dutchess Community College guarantees a consistent pool of prospective commercial and residential tenants. With its established ground-floor income, expansive raw upper floors, and prime arterial location, 354 Main Street represents a premier rehabilitation project ready for immediate transformation.
| 3 days ago | Status changed to Active | |
| 3 days ago | Price changed to $450,000 | |
| 3 days ago | Listing updated with changes from the MLS | |
| 4 days ago | Listing first seen on site |
Based on information submitted to the MLS GRID as of 2026-11-04 11:09 PM EST. All data is obtained from various sources and may not have been verified by broker or MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.